Brazilian researchers compared the most frequently used treatments for tinnitus, which affects about 750 million people worldwide.
Low-level laser therapy and its associated photobiomodulation, according to a study comparing the main treatments currently in use, conducted by Brazilian scientists at the Center for the Research of Optics and Photonics (CEPOF), It is said to be the most effective treatment for tinnitus known. The study is reported in an article published in the journal. Personalized Medicine Journal.
CEPOF is a Research, Innovation and Dissemination Center (RIDC) funded by FAPESP and hosted by the Institute of Physics of San Carlos, University of São Paulo (IFSC-USP), Brazil.
About 750 million people worldwide suffer from tinnitus, according to a European study that analyzed patient data over 50 years. Often described as ringing or hissing in the ears, it is considered a symptom rather than a disease, but it is uncomfortable and sometimes disabling. Known causes range from earwax build-up and insufficient peripheral cleaning of the inner ear to brain injury and bruxism. There is no standard treatment or drug approved by the US Food and Drug Administration (FDA).
“Tinnitus is a very widespread condition throughout the general population. different results,” said CEPOF researcher Vitor Hugo Panoca. “After finding articles in the scientific literature showing consistent laser treatment results, we decided to compare the main treatments and pursue further responses to the problem.”
Over the course of four weeks, Panyoka and his team randomized more than 100 men and women aged 18-65 into 10 groups to provide alternative and complementary treatments for idiopathic (no apparent cause) and refractory tinnitus. tested the remedy. The treatments tested included laser acupuncture, flunarizine dihydrochloride, ginkgo (medicinal plants), and low-level laser stimulation of the inner or outer auditory canal (transmembrane stimulation) alone or in combination with vacuum therapy, ultrasound therapy. G. Bilova or flunarizine dihydrochloride.
Patients received eight treatment sessions twice weekly. They were clinically assessed using the ‘Tinnitus Handicap Inventory Questionnaire’ containing a total of 25 questions before treatment initiation, after the 8th session, and 2 weeks later. A functional subscale consisted of 11 questions about mental, social, occupational, and physical limitations due to tinnitus.
The best outcomes were observed in patients treated with laser acupuncture alone and transmuscular low-intensity laser stimulation alone. In the latter case, increasing the irradiation time from 6 min to 15 min improved further.a combination of laser therapy and vacuum therapy, or G. Bilovalaser acupuncture alone, and flunarizine dihydrochloride alone also had sustained therapeutic effects.
“Positive effects include anti-inflammatory and relaxing effects. We believe we can increase peripheral irrigation that is effective,” Pahoka said.
The CEPOF study isn’t the only study to show that laser treatment can improve the condition of tinnitus patients, but it could pave the way for protocols to be used by dentists, otolaryngologists, speech pathologists, and other healthcare professionals. Open The number of sessions and intensity of treatment vary widely in the literature, so consult with a practitioner with such patients.
“Understanding how successful treatments work will help us focus on the most productive approaches for future research. It’s part of the learning curve,” Panyoka said, adding that the long-term effects of laser treatments also need to be investigated.
Reference: “Effects of red and infrared laser therapy in patients with tinnitus: a double-blind clinical randomized controlled study combining light and ultrasound, drug and vacuum therapy.” Vitor Hugo Panhóca, Antônio Eduardo de Aquino Junior, Viviane Brocca de By Souza, Simone Aparecida Ferreira, Lais Tatian Ferreira, Carina Julienne de Oliveira Souza, Patricia Jericho Tamae, Marcelo Saito Nogueira, Vanderlei Salvador Bagnato, March 26, 2023 , Personalized Medicine Journal.
FAPESP also supported this research through a postdoctoral fellowship awarded to Fernanda Rossi Paolillo.
The study was conducted by researchers at the Irmandade Santa Casa de Misericordia Hospital in San Carlos, the University of Central São Paulo (UNICEP), the Center for Integrative Therapy in Londrina (State of Paraná), Brazil, and the Tyndall National Institute at University College. It was conducted jointly with Cork, Ireland (UCC).
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